Inside the Chamber of Secrets of the Type III Secretion System
نویسنده
چکیده
The bacterial type III secretion system is a specialized machine that injects effectors into eukaryotic cells to manipulate the host cell physiology. In this issue of Cell, Hu et al. use cryo-electron tomography to reveal an unprecedented level of details regarding the architecture of this machine and the conformational changes that occur during its assembly.
منابع مشابه
فراوانی ژنهای کد کننده سیتوتوکسینهای exoT، exoY، exoS وexoU سیستم ترشحی تیپ 3 در سودوموناس آئروجینوزا جدا شده از بیماران سوختگی
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متن کاملThe type III secretion system is involved in Escherichia coli K1 interactions with Acanthamoeba.
The type III secretion system among Gram-negative bacteria is known to deliver effectors into host cell to interfere with host cellular processes. The type III secretion system in Yersina, Pseudomonas and Enterohemorrhagic Escherichia coli have been well documented to be involved in the bacterial pathogenicity. The existence of type III secretion system has been demonstrated in neuropathogenic ...
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عنوان ژورنال:
- Cell
دوره 168 شماره
صفحات -
تاریخ انتشار 2017